Cannabidiol (CBD) is one of the naturally occurring cannabinoids found in cannabis plants.
In most cases, products with CBD are considered to be food supplements that are recommended for daily consumption, in order to restore the tired body, improve your well-being and supplement your diet with the right ingredients.
CBD (Cannabidiol ) and THC (Tetrahydrocannabinol) are the most well-known cannabinoids in the cannabis plant, mostly found in flowers of the plant. THC, which causes psychoactive effects, is strictly controlled. In most countries, the usage of products high in THC is only possible with strict control and supervision.
CBD, unlike THC, does not appear to have any psychotropic (“high”) effects, (i.e., CBD is not intoxicated, does not cause dizziness or euphoria) and is not prohibited or strictly controlled.
It is impossible to overdo with CBD, it is not possible to poison or otherwise harm yourself. The World Health Organization, based on the latest scientific sources, emphasizes that even a 1500 mg CBD is completely tolerated by humans or animals, without any health-related side effects. Very high levels can cause dry mouth, drowsiness, and may reduce blood pressure. But there is no need to consume as much CBD as possible. Usually, less means more.
CBD has a weak effect on the cannabinoid receptor CB1 and CB2, but this cannabinoid acts well on the GPR55 and the serotonin receptor 5-HT1A and is valuable for many other properties.
CBD has strong anti-inflammatory, neuroprotective, antibacterial, anti-fungal properties. Suppresses the spread of cancerous or mutated cells and promotes apoptosis, perfectly helps to remove toxins from the body, and strengthens the immune system.
CBD has strong antipsychotic properties and is therefore widely used to reduce depression, anxiety, aggression, and anger.
In 2015, the journal “Pharmacology and Pharmacy” published a research study where it was stated that full-spectrum cannabis flower extracts are much more effective than isolated CBD in alleviating symptoms of certain disorders.
The full range of cannabis flower extracts contains other cannabinoids, such as terpenes, flavonoids, and other natural substances that work together synergistically, reinforcing each other’s effects and promoting better bioavailability.
NOTE! The content of THC in We Are Canna products does not exceed the Dutch limit of 0.05%.
YES! CBD products are completely legal and safe. Because of its own safety, Cannabidiol (CBD) has never been banned or controlled, but in some countries, certain restrictions apply to products containing parts of herbal cannabis.
“The CBD is not included in 1961, 1971, or 1988 United Nations Single Convention on Narcotic Drugs. The CBD is also not included in the 1961, 1971 in 1988 United Nations Contracts for the Control of Drugs.”
– CANNABIDIOL (CBD) Critical Review Report The Expert Committee on Drug Dependence Fortieth Meeting Geneva, 4-7 June 2018.
“CBD is a good tolerant and safe substance for the human body. There are no reports of overdose or poisoning. Until today, there is no data on the reactive use of CBD or any other public health issues associated with the use of isolated CBD. In controlled studies, no signs of addiction or withdrawal were noted for the potential dependence of cannabidiol.”- CANNABIDIOL (CBD) Critical Review Report The Expert Committee on Drug Dependence Fortieth Meeting Geneva, 4-7 June 2018
The use of Cannabidiol (CBD) in animals is completely safe. Furthermore, cannabidiol and other cannabinoids can improve the quality of your pet’s life.
All living organisms, including humans, have an endocannabinoid system. The body of an animal also naturally produces endocannabinoids that regulate the metabolism process, control the functioning of the immune system, organ activity, emotional state, development and proper internal balance of the body.
Sometimes, due to various reasons, the body begins to stop producing sufficient endocannabinoids, which affects the general condition or promotes the occurrence of certain disorders.
CBD and other phytocannabinoids naturally occurring in cannabis are the most appropriate supplement to human’s as well as your pet’s body at the time when endocannabinoid deficiency occurs.
Note! Animals are recommended for extremely small amounts of CBD.
Terpenes (terpenoids) – organic aromatic and flavour compounds found in many plants and even in some insects.
Plants produce terpenes to repel predators and lure pollinators. Terpenes are also responsible for plant regeneration and oxygenation.
In the cannabis plant, terpenes are produced in trichomes (small hairs) located on the hemp flower. Phytocannabinoids such as CBDA, THCA, CBGA, etc. are also produced there. Accordingly, following the decarboxylation process, these cannabinoids are converted to CBD, THC, CBG and the like.
Different strains of cannabis form different terpenes, making each strain unique. Essential oils are based on terpenes.
One of the most prominent cannabis researchers, neuroscientist Ethan Russo, in his report from 2011 stated, that Terpenes, in their interaction with cannabinoids, modulate each other’s effects, improve endocannabinoid function and provide certain therapeutic properties (source).
There are a huge variety of terpenes, and they are valued for their anti-inflammatory, antibacterial, antifungal, analgesic, anti-cancer, antioxidant, appetite-stimulating properties.
Thousands of flavonoids are found in nature, mainly in various fruits, vegetables, flowers and other plants. Flavonoids belong to a class of plant secondary metabolites having a polyphenolic structure.
The word “flavonoid” is derived from the Latin word “flavus” which means yellow. The primary function of flavonoids in plants is to provide colour pigmentation to plants. Flowers attract pollinators by their colours, fruits and vegetables indicate when they are fit for consumption, whereas hemp flavonoids colour the flowers and leaves in a variety of colours.
Flavonoids also protect the plant from UV radiation, pests and various diseases.
The unique flavonoids that develop only in cannabis are called cannaflavins.
They are pharmacologically active and continuously studied. Canaflavin A has been shown to reduce inflammation by inhibiting the inflammatory molecule PGE-2. Thus it is about 30 times more effective than aspirin.
The use of flavonoids is known to reduce the development of certain breast and lung cancers due to their potent anti-inflammatory properties.
Just like the cannabidiol “CBD, flavonoids modulate the effect of tetrahydrocannabinol “THC”. Because of their complex biochemical mechanisms, flavonoids interact in different parts of the human body – some interact with estrogen receptors, others act as potent antioxidants or inhibit negative enzymatic processes.
Flavonoids and terpenoids contribute to the effects of phytocannabinoids while creating an entourage effect. Together, these substances enhance each other’s effects and provide the therapeutic properties of different cannabis products. The composition of our products is formulated to maintain the most natural and diverse composition of phytoactive substances. Therefore, the accompanying effect and interaction between the components are especially important to us.
In 1990, when scientists studied the effects of THC on the human body, they have discovered a complex, all-inclusive system and certain receptors, that react to phytocannabinoids that occur naturally in cannabis. This system was called “Endogenous Cannabinoid System” or “Endocannabinoid System (ECS)”.
The endocannabinoid system is highly complex. Developed throughout the body, it transmits various signals, regulating the activity of other internal systems and organs. Its main purpose is Homeostasis – proper maintenance of the body’s internal processes.
Scientists do not fully understand yet how exactly this system works and what its full potential is. So far, it is known to be one of the most important systems in our body that regulate such functions and processes as:
- Appetite and digestion
- Reproduction and fertility
- Immune protection
- Reduction of inflammation (including neuroinflammation)
- Motor control
- A sensation of pain (pain relief)
- Body temperature
- A feeling of pleasure
- Proper functioning of the cardiovascular system
- Bone mass formation and growth
This system consists of:
1. Endocannabinoids – cannabinoids that are naturally produced in our body. Two endocannabinoids that are the most analysed so far:
- Anandamide (AEA)
- 2-arachidonoylglyerol (2-AG)
The body produces endocannabinoids when needed and as much as needed. The endocannabinoid system is active and cannabinoid receptors are stimulated by endocannabinoids even if you don’t use cannabis.
2. Cannabinoid receptors – receptors found throughout the whole human body. Agonists or antagonists at these receptors include endocannabinoids (naturally produced by the human body), phytocannabinoids (cannabinoids commonly found in cannabis), and synthetic cannabinoids (human-made cannabinoids).
The two main receptors of the endocannabinoid system are:
- CB1 – receptors that are mainly found in the central nervous system (CNS).
- CB2 – receptors that are mainly found in the peripheral nervous system, especially in the immune system.
Cannabinoids react with all cannabinoid receptors. The result of the interaction depends on which receptor and which cannabinoid it stimulates / blocks.
3. Enzymes – responsible for breaking down cannabinoids once they’ve carried out their function.
- Fatty acid amide hydrolase – which breaks down Anandamide AEA
- Monoacylglycerol acid lipase – which breaks down 2-Arachidonoylglycerol 2-AG.
“Relax, eat, sleep, forget and protect.” – it is a description of the functions in the endocannabinoid system of the renowned cannabis scientist Professor Di Marzo.
Endocannabinoid deficiency can lead to clinical endocannabinoid deficiency syndrome, which can be the cause of many ailments. Cannabinoids in cannabis help maintain the body’s proper functioning, protection and development (source).